Invasive fungal disease in specific at-risk patients

Invasive fungal disease in PICU: epidemiology and risk factors

Candida and Aspergillus spp. are the most common agents responsible for invasive fungal infections in children. They are associated with a high mortality and morbidity rate as well as high health care costs. An important increase in their incidence has been observed during the past two decades. In infants and children, invasive candidiasis is five times more frequent than invasive aspergillosis...

Risk factors for invasive fungal disease in critically ill adult patients: a systematic review

INTRODUCTION Over 5,000 cases of invasive Candida species infections occur in the United Kingdom each year, and around 40% of these cases occur in critical care units. Invasive fungal disease (IFD) in critically ill patients is associated with increased morbidity and mortality at a cost to both the individual and the National Health Service. In this paper, we report the results of a systematic ...

Invasive Fungal Disease highlighted at the 22 nd European Congress

Dr Klaassen reported results of a recent study in which a novel mixed-format real-time polymerase chain reaction (PCR) assay was used to identify wild type cyp51A and point mutations conferring azole resistance in A. fumigatus isolates. Hybridisation of a single strand DNA detection probe with single strand target gene DNA enabled the researchers to differentiate between susceptible and resista...

β-glucan in the diagnosis of invasive fungal disease

Invasive Fungal Infections in ALL Patients